H

HDAC:

stands for histone deacetylase; Connections Map Component -- Histone deacetylase

HEAT:

stands for Huntington-elongation factor 1A-protein phosphatase 2A (PP2A) A subunit-TOR repeats; each ~39 amino-acid repeat is believed to form antiparallel a helices that stack in parallel with other repeats to form an ordered array, which may serve to mediate protein-protein interactions

HECT:

stands for homology to the papillomavirus E6-associated protein C terminus; defines a family of E3 ubiquitin ligases; Connections Map Component -- Smad ubiquitin regulatory factor

HGF:

stands for hepatocyte growth factor; also known as scatter factor; a secreted protein ligand; Connections Map Component -- Met

HHL:

stands for N-hexanoyl-L-homoserine; a diffusible quorum signal

HID:

stands for head involution defective; a Drosophila antagonist of inhibitor of apoptosis proteins (IAPs), promotes caspase activation, leading to programmed cell death

HIPK:

stands for homeodomain-interacting protein kinase; a serine-threonine protein kinase

hKIS:

stands for human kinase interacting with stathmin; one substrate is the cyclin-dependent kinase inhibitor p27

HMG:

stands for high mobility group; an HMG box is a motif found in certain transcription factors; Connections Map Components -- T cell factor | Lymphoid-enhancing factor 1 | Sox

hnRNA:

stands for heterogeneous nuclear ribonucleic acids; unspliced pre-messenger RNA (pre-mRNA)

hnRNP:

stands for heterogeneous nuclear ribonucleoproteins; RNA binding proteins that complex with heterogeneous nuclear ribonucleic acids (hnRNA); Connections Map Component -- Ribonucleoprotein K

HO-1:

stands for heme oxygenase 1, an inducible isoform of the enzyme that converts heme to biliverdin-IX and also produces the signaling gas carbon monoxide (CO)

HO-2:

stands for heme oxygenase 2, a constitutively expressed isoform of the enzyme that converts heme to biliverdin-IX and also produces the signaling gas carbon monoxide (CO)

HPK1:

stands for hematopoietic progenitor kinase 1

HPLC:

stands for high-pressure liquid chromatography

HPt:

stands for histidine-containing phosphotransfer protein; mediates the transfer of phosphate to histidine in His-Asp-His-Asp phosphorelay signaling systems; Connections Map Component -- Histidine phosphotransfer protein

HRG:

stands for heregulin; a secreted ligand that binds members of the epidermal growth factor receptor family

HRI:

stands for heme-regulated inhibitor; a hemin binding kinase activated by autophosphorylation in response to hemin deficiency

HSE:

stands for heat shock element

HSP:

stands for heat shock protein; proteins in this family participate in cellular responses to heat and other stresses; Connections Map Components -- Heat shock protein 27 kD | Heat shock protein 90 kD

HUVEC:

stands for human umbilical vascular (or vein) endothelial cells

HVEM:

stands for herpes virus entry mediator