L

LAM:

stands for lipoarabinomannan; a microbial product recognized by Toll-like receptor 2 (TLR-2)

LAT:

stands for linker for activation of T cells; an adaptor; Connections Map Component -- Linker of activated T cells

LBP:

stands for lipopolysaccharide-binding protein; a serum protein involved presentation of microbial lipopolysaccharides to immune system

LC:

stands for liquid chromatography

Lck:

a Src family protein tyrosine kinase; Connections Map Components -- Lck -associated adaptor protein | Lck

LEF-1:

stands for lymphoid enhancer factor 1; a transcription factor; Connections Map Component -- Lymphoid-enhancing factor 1

LFA-1:

stands for lymphocyte function-associated antigen-1; also known as Lβ2; an integrin

LGIC:

stands for ligand-gated ion channel

LIF:

stands for leukemia inhibitory factor, a secreted protein that contributes to glial differentiation

LIMK:

stands for LIM kinase; a serine, threonine kinase containing the protein interaction domain known as LIM; mammalian LIMK1 and DLIMK1, the Drosophila homolog, have two LIM domains and a PDZ domain and are activated by type II bone morphogenic protein (BMP) receptors

LMB1:

stands for leptomycin B; a pharmacological inhibitor of the exportin CRM1

LMP1:

stands for Epstein-Barr virus latent membrane protein 1

Lnk:

the founding member of a family of adaptor proteins; Connections Map Component -- APS

LOH:

stands for loss of heterozygosity

LPA:

stands for lysophosphatidic acid; a water-soluble phospholipid; Connections Map Component -- Lysophosphophatidic acid

LPS:

stands for lipopolysaccharide; microbial LPS can activate Toll-like receptors (TLRs)

LRAT:

stands for lecithin retinol acyl transferase; an enzyme that esterifies Vitamin A

LRP:

stands for low density lipoprotein (LDL) receptor-related protein; members of this family can serve as nutrient receptors or participate in signaling cascades; Connections Map Component -- Low-density lipoprotein receptor-related protein

LRR:

stands for leucine-rich repeat

LTA:

stands for lipoteichoic acid; a microbial product that can activate Toll-like receptors (TLRs)

LTD:

stands for long-term depression; a prolonged inhibition of neuronal synaptic activity

LTP:

stands for long-term potentiation; a prolonged enhancement of neuronal synaptic activity

LTR:

stands for long terminal repeat; a DNA sequence that enhances transcription