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In the Current Issue 30 June 2009 (Issue 77)

Adhesion proteins in lamellae

Adhesion proteins in lamellae

Editorial Guide

Challenging Times
Michael B. Yaffe
Abstract  |  Full Text  |  PDF

Research Articles

Therapeutically Targeting ErbB3: A Key Node in Ligand-Induced Activation of the ErbB Receptor–PI3K Axis
Birgit Schoeberl, Emily A. Pace, Jonathan B. Fitzgerald, Brian D. Harms, Lihui Xu, Lin Nie, Bryan Linggi, Ashish Kalra, Violette Paragas, Raghida Bukhalid, Viara Grantcharova, Neeraj Kohli, Kip A. West, Magdalena Leszczyniecka, Michael J. Feldhaus, Arthur J. Kudla, and Ulrik B. Nielsen
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

PKCε Regulation of an α5 Integrin–ZO–1 Complex Controls Lamellae Formation in Migrating Cancer Cells
Saara Tuomi, Anja Mai, Jonna Nevo, Jukka O. Laine, Vesa Vilkki, Tiina J. Öhman, Carl G. Gahmberg, Peter J. Parker, and Johanna Ivaska
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

Perspective

AIMing 2 Detect Foreign DNA
Arthur M. Krieg
Abstract  |  Full Text  |  PDF

Podcast

Science Signaling Podcast: 30 June 2009
Ulrik B. Nielsen and Annalisa M. VanHook
Abstract  |  Full Text  |  Podcast

Glossary

Find out what ERM, FMN, and LH mean in the world of cell signaling.
New Terms  |  Search and Browse the Glossary

Editors' Choice

Really Random Receptors
D. Greenfield et al., PLoS Biol. 7, e1000137 (2009).
Read this Summary  |  Read all Summaries

In Literature

What's Hot
Read this highly accessed article published recently in a previous issue: Deciphering Signaling Outcomes from a System of Complex Networks Abstract  |  Full Text
Virtual Journal
Check out this article, just added to the Virtual Journal: The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis Abstract  |  Full Text  |  Search and browse the Virtual Journal
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Issue Archive
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In Community

Events, Meeting Reports, and Presentations
Check out the calendar, read highlights, and view presentations of cell signaling meetings and conferences.
Directory
Featured person: Sekar Natesampillai. Find collaborators and people with shared research interests—join the Signaling community and add your information to the Directory!
Forums
Share highlights from signaling meetings, read the announcement about award-winning talks in the Meeting Highlights.
E-Letters
Featured E-Letter: Paradigm Shift. Find out how to submit a comment to make Science Signaling a rich community by contributing your knowledge. For example, share your experiences with a method described in a Protocol; tell other teachers how you used Teaching Resources; alert the community to research related to those highlighted in Editors' Choice; comment on or ask the authors about their articles.

In Resources

Teaching Resources
More than 50 different resources provide information for course planning, lecture notes, slides, and animations.
Glossary
Find out what those acronyms and abbreviations mean. Browse or search the glossary of cell signaling terms. Look at the list of the most recently added terms.
Podcasts
Tune-in for a portable and understandable summary of selected cell signaling research. Check out each episode of the Science Signaling Podcast.
ST NetWatch
Featured in Modeling Tools: MCell. Explore the sites selected by the editors or submit your favorite signal transduction Web site.
Funding Sources
Check out the opportunities for funding cell signaling research and training.
Jobs
Search or browse employment opportunities related to signal transduction in Science Careers.

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