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In the Current Issue 15 April 2014 (Issue 321)

Research Articles

The C-Terminal SH3 Domain Contributes to the Intramolecular Inhibition of Vav Family Proteins
María Barreira, Salvatore Fabbiano, José R. Couceiro, Eva Torreira, Jorge L. Martínez-Torrecuadrada, Guillermo Montoya, Oscar Llorca, and Xosé R. Bustelo
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

Intronic miR-3151 Within BAALC Drives Leukemogenesis by Deregulating the TP53 Pathway
Ann-Kathrin Eisfeld, Sebastian Schwind, Ravi Patel, Xiaomeng Huang, Ramasamy Santhanam, Christopher J. Walker, Joseph Markowitz, Kevin W. Hoag, Tiina M. Jarvinen, Benjamin Leffel, Danilo Perrotti, William E. Carson III, Guido Marcucci, Clara D. Bloomfield, and Albert de la Chapelle
Editor's Summary  |  Abstract  |  Full Text  |  PDF  |  Supplementary Materials

Podcast

Science Signaling Podcast: 15 April 2014
Ann-Kathrin Eisfeld, Albert de la Chapelle, and Annalisa M. VanHook
Abstract  |  Full Text  |  Podcast

Editors' Choice

T Cells Hurt the Brain
B. D. S. Clarkson et al., J. Exp. Med. 211, 595–604 (2014).
Read this Summary  |  Read all Summaries

In Literature

What's Hot
Read this highly accessed article published recently in a previous issue:
β1 Integrin Inhibition Elicits a Prometastatic Switch Through the TGFβ–miR-200–ZEB Network in E-Cadherin–Positive Triple-Negative Breast Cancer
Abstract  |  Full Text
Virtual Journal
Check out this article, just added to the Virtual Journal:
The Serine/Threonine Kinase Ndr2 Controls Integrin Trafficking and Integrin-Dependent Neurite Growth
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In Community

Meeting Reports and Presentations
Read highlights and view presentations of cell signaling meetings and conferences.
Directory
Featured person: A. J. Ghalayini. Find collaborators and people with shared research interests—join the Signaling community and add your information to the Directory!
Forums
Share highlights from signaling meetings or read the recent posting "Linking Cancer and Metabolism" in Meeting Highlights.
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In Resources

Teaching Resources
Featuring the course "Systems Biology—Biomedical Modeling," explore this and other materials for teachers.
Glossary
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Podcasts
Tune-in for a portable and understandable summary of selected cell signaling research. Check out each episode of the Science Signaling Podcast.
ST NetWatch
Featured in Bioinformatics Resources: cBio Cancer Genomics Portal. Explore the sites selected by the editors or submit your favorite signal transduction Web site.
Jobs
Search or browse employment opportunities related to signal transduction in Science Careers.

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