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Letters Archive

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  • January 2012 (2)
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Recent Letters

Cell Biology
Response to Comment on "A Dynamic Network Model of mTOR Signaling Reveals TSC-Independent mTORC2 Regulation": Building a Model of the mTOR Signaling Network with a Potentially Faulty Tool
Piero Dalle Pezze, Annika G. Sonntag, Daryl P. Shanley, and Kathrin Thedieck (10 July 2012)
Sci. Signal. 5 (232), lc4. [DOI: 10.1126/scisignal.2003224]
Dalle Pezze et al. respond to criticisms regarding the specificity of phosphorylation of Ser2481 of mTOR as a specific readout of mTORC2 activity. Abstract »   Full Text »   PDF »  
Cell Biology
Comment on "A Dynamic Network Model of mTOR Signaling Reveals TSC-Independent mTORC2 Regulation": Building a Model of the mTOR Signaling Network with a Potentially Faulty Tool
Brendan D. Manning (10 July 2012)
Sci. Signal. 5 (232), lc3. [DOI: 10.1126/scisignal.2003250]
Manning questions whether the biochemical readout used to test the network models is sufficiently specific. Abstract »   Full Text »   PDF »  

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