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Perspectives Archive

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Structural Biology
Revisiting Channel Allostery: A Coherent Mechanism in IP3 and Ryanodine Receptors
Kozo Hamada and Katsuhiko Mikoshiba (22 May 2012)
Sci. Signal. 5 (225), pe24. [DOI: 10.1126/scisignal.2003148]
Structural analyses suggest a similar gating mechanism in the IP3 and ryanodine receptors. Abstract »   Full Text »   PDF »  
Structural Biology
Structure of the First Sphingosine 1-Phosphate Receptor
Abby L. Parrill, Santiago Lima, and Sarah Spiegel (22 May 2012)
Sci. Signal. 5 (225), pe23. [DOI: 10.1126/scisignal.2003160]
The lipid sphingosine 1-phosphate may laterally diffuse through the membrane to bind a receptor. Abstract »   Full Text »   PDF »  

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