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Perspectives Archive

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Cell Biology
An "Inordinate Fondness for Transporters" Explained?
David J. Eide (7 February 2012)
Sci. Signal. 5 (210), pe5. [DOI: 10.1126/scisignal.2002837]
The presence of low- and high-affinity transporters enables cells to adequately prepare for nutrient fluctuations. Abstract »   Full Text »   PDF »  
Neuroscience
Depletion of Extracellular Ca2+ Prompts Astroglia to Moderate Synaptic Network Activity
Dmitri A. Rusakov (24 January 2012)
Sci. Signal. 5 (208), pe4. [DOI: 10.1126/scisignal.2002799]
Reduced extracellular calcium stimulates astrocytes to release adenosine triphosphate, which activates inhibitory neurons and may limit excitability. Abstract »   Full Text »   PDF »  

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