Glossary: B
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B
- Bad:
- stands for Bcl-2/Bcl-XL-associated death promotor, also known as BAD; a pro-apoptotic Bcl-2 family member, a death agonist; Connections Map Components -- Bcl-xL | Bcl-w | BAD
- BAR:
- stands for bifunctional apoptosis regulator; an antiapoptotic adaptor protein; Connections Map Component -- Bifunctional apoptosis regulator
- Bax:
- a pro-apoptotic Bcl-2 family member, a death agonist; Connections Map Components -- Bax Inhibitor-1 | Bax
- Bcl-2:
- stands for B cell lymphoma/leukemia 2; (1) a family of apoptosis-related proteins, which includes pro-apoptotic members Bax, Bad, and Bak and anti-apoptotic members Bcl-2, Bcl-XL, Mcl-1, Bcl-w, or A1; (2) the anti-apoptotic Bcl-2 family member known as Bcl-2, a death antagonist; Connections Map Components -- Bcl-xL | Bcl-w | Bcl-b | B cell lymphoma-2
- Bcl-XL:
- an antiapoptotic Bcl-2 family member (BCL-XL), a death antagonist; Connections Map Component -- Bcl-xL
- Bcl10:
- an adaptor protein with a caspase recruitment domain (CARD)
- BCMA:
- stands for B cell maturation antigen
- BCR:
- stands for B cell receptor; Connections Map Component -- B cell antigen receptor
- beta-AR:
- stands for β-adrenergic receptor (β-AR); a family of G protein-coupled receptors that bind adrenaline (epinephrine) and noradrenaline (norepinephrine); Connections Map Component -- beta-Adrenergic receptor
- beta-arrestin:
- β-arrestin; a negative regulator of some classes of G protein-coupled receptors, a signaling scaffold for G protein signaling; Connections Map Component -- Arrestin
- beta-TrCP:
- stands for beta transducin repeat-containing protein (β-TrCP); an F-box protein that is a component of some Skp-cullin-F-box (SCF) ubiquitin ligase complexes; Connections Map Component -- beta-transducin repeat containing protein
- betagamma:
- also known as Gβγ; the βγ heterodimer of heterotrimeric guanine nucleotide-binding proteins (G proteins); Connections Map Component -- G beta/gamma
- BH:
- (1) stands for Bcl-2 homology; a set of signature protein interaction motifs (BH1, BH2, BH3, and BH4) that define protein families involved in the regulation of apoptosis; (2) stands for Bruton`s tyrosine kinase (Btk) homology, a protein domain
- BHL:
- stands for N-butanoyl-L-homoserine; a bacterial quorum signaling molecule
- bHLH:
- stands for basic helix-loop-helix; a protein motif frequently found in transcription factors
- BIC:
- B-cell integration complex
- biotin-HPDP:
- stands for N-[6-(biotinamido)hexyl]-3′-(2′-pyridyldithio)propionamide
- BIR:
- stands for baculovirus inhibitor of apoptosis (IAP) repeat; a 70-amino acid repeat that defines the IAP family of antiapoptotic regulators
- BisPA:
- stands for bisphosphatidic acid; a four-fatty-acid chain lipid that can induce membrane curvature and vesiculation
- BMK1:
- stands for big mitogen-activated protein kinase 1, also known as extracellular signal-regulated kinase 5 (ERK5) or mitogen-activated protein kinase 7 (MAPK7); a serine-threonine protein kinase; Connections Map Component -- Mitogen-activated protein kinase 7
- BMP:
- stands for bone morphogenetic protein; Connections Map Component -- Bone morphogenetic protein
- BMPR:
- stands for bone morphogenetic protein receptor; Connections Map Component -- Bone morphogenetic protein receptor II
- BrdU:
- stands for 5-bromo-2′-deoxyuridine; a reagent used to measure cell division
- BRET:
- stands for bioluminescence resonance energy transfer
- Btk:
- stands for Bruton's tyrosine kinase; a protein tyrosine kinase; Connections Map Components -- TEC Family | Bruton tyrosine kinase
- BZD:
- stands for benzodiazepine; class of drugs used to treat insomnia and anxiety that bind to GABAA receptors
- bZIP:
- basic leucine zipper; a protein motif frequently found in transcription factors; Connections Map Components -- CHOP10 | cAMP response element binding protein | ATF1
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