Glossary: L
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L
- LAM:
- stands for lipoarabinomannan; a microbial product recognized by Toll-like receptor 2 (TLR-2)
- LAT:
- stands for linker for activation of T cells; an adaptor; Connections Map Component -- Linker of activated T cells
- LBP:
- stands for lipopolysaccharide-binding protein; a serum protein involved presentation of microbial lipopolysaccharides to immune system
- LC:
- stands for liquid chromatography
- Lck:
- a Src family protein tyrosine kinase; Connections Map Component -- Lck
- LCR:
- stands for locus control region; a region of DNA that enhances the expression of groups of genes through long-range interactions, often mediated by chromosomal looping
- LEF-1:
- stands for lymphoid enhancer factor 1; a transcription factor; Connections Map Component -- Lymphoid-enhancing factor 1
- LFA-1:
- stands for lymphocyte function-associated antigen-1; also known as
Lβ2; an integrin
- LGIC:
- stands for ligand-gated ion channel
- LIF:
- stands for leukemia inhibitory factor, a secreted protein that contributes to glial differentiation
- LIMK:
- stands for LIM kinase; a serine, threonine kinase containing the protein interaction domain known as LIM; mammalian LIMK1 and DLIMK1, the Drosophila homolog, have two LIM domains and a PDZ domain and are activated by type II bone morphogenic protein (BMP) receptors
- LMB1:
- stands for leptomycin B; a pharmacological inhibitor of the exportin CRM1
- LMP1:
- stands for Epstein-Barr virus latent membrane protein 1
- Lnk:
- the founding member of a family of adaptor proteins; Connections Map Component -- APS
- LOH:
- stands for loss of heterozygosity
- LPA:
- stands for lysophosphatidic acid; a water-soluble phospholipid; Connections Map Component -- Lysophosphophatidic acid
- LPR1:
- stands for lipid phosphatase-related protein 1; an integral membrane protein involved in filopodium formation
- LPS:
- stands for lipopolysaccharide; microbial LPS can activate Toll-like receptors (TLRs)
- LRAT:
- stands for lecithin retinol acyl transferase; an enzyme that esterifies Vitamin A
- LRP:
- stands for low density lipoprotein (LDL) receptor-related protein; members of this family can serve as nutrient receptors or participate in signaling cascades; Connections Map Component -- Low-density lipoprotein receptor-related protein
- LRR:
- stands for leucine-rich repeat
- LTA:
- stands for lipoteichoic acid; a microbial product that can activate Toll-like receptors (TLRs)
- LTD:
- stands for long-term depression; a prolonged inhibition of neuronal synaptic activity
- LTP:
- stands for long-term potentiation; a prolonged enhancement of neuronal synaptic activity
- LTR:
- stands for long terminal repeat; a DNA sequence that enhances transcription
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