Science Signaling http://stke.sciencemag.org/ Science Signaling, the Signal Transduction Knowledge Environment American Association for the Advancement of Science Nancy Gough (mailto:ngough@aaas.org) Copyright 2010 American Association for the Advancement of Science 2010-02-09T15:17:48-05:00 en Science http://www.sciencemag.org/icons/banner/title.gif http://www.sciencemag.org [Research Article] ARD1 Stabilization of TSC2 Suppresses Tumorigenesis through the mTOR Signaling Pathway http://stke.sciencemag.org/cgi/content/abstract/3/108/ra9?rss=1 Acetylation by ARD1 of an inhibitor of mammalian target of rapamycin may inhibit cancer growth. Hsu-Ping Kuo, Dung-Fang Lee, Chun-Te Chen, Mo Liu, Chao-Kai Chou, Hong-Jen Lee, Yi Du, Xiaoming Xie, Yongkun Wei, Weiya Xia, Zhang Weihua, Jer-Yen Yang, Chia-Jui Yen, Tzu-Hsuan Huang, Minjia Tan, Gang Xing, Yingming Zhao, Chien-Hsing Lin, Shih-Feng Tsai, Isaiah J. Fidler, and Mien-Chie Hung [Research Article] SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor http://stke.sciencemag.org/cgi/content/abstract/3/108/ra10?rss=1 Attachment of SUMO lets insulin-like growth factor receptors act as transcriptional regulators in the nucleus. Bita Sehat, Ali Tofigh, Yingbo Lin, Eric Trocmé, Ulrika Liljedahl, Jens Lagergren, and Olle Larsson [Perspective] Glucocorticoid Receptor DNA Binding Decoy Is a Gas http://stke.sciencemag.org/cgi/content/abstract/3/108/pe5?rss=1 By mimicking a DNA response element, a noncoding RNA inhibits glucocorticoid receptor activity. Michael J. Garabedian and Susan K. Logan [Funding Sources] Find grants, fellowships, and other opportunities for cell signaling research. http://stke.sciencemag.org/resources/funding/?rss=1 [Editors' Choice] http://stke.sciencemag.org/cgi/content/abstract/3/108/ec45?rss=1 Database of Cell Signaling http://stke.sciencemag.org/cgi/cm/stkecm;CMP_7006?rss=1 Estrogen Receptor Pathway