Contents
Vol 14, Issue 672
Research Articles
- SOX9 is required for kidney fibrosis and activates NAV3 to drive renal myofibroblast function
Loss of the transcription factor SOX9 reduces experimentally induced kidney fibrosis in mice.
- A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability
A pathway underlying the TNFα-induced decrease in endothelial barrier function is found in veins but not arteries.
Editors' Choice
- Messaging by mitochondria
Intercellular mitochondrial transfer promotes metabolic homeostasis and stimulates wound healing.
About The Cover

Online Cover This week features a Research Article that identifies roles for SOX9 and NAV3 in promoting renal fibrosis in both mice and humans and suggests pericytes as a potential source of myofibroblasts in renal fibrosis. The image shows scar tissue (blue) in a fibrotic kidney. [Image: Vetpathologist/Shutterstock]