Contents
16 July 2019
Vol 12, Issue 590
Vol 12, Issue 590
Research Articles
- Galectin-3 initiates epithelial-stromal paracrine signaling to shape the proteolytic microenvironment during corneal repair
Epithelia-fibroblast contact promotes paracrine signaling that stimulates matrix remodeling during corneal repair.
- Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer
CDK9 inhibitors may treat KRAS-mutant cancers by inducing MYC protein degradation.
Editors' Choice
- How vitamin A protects the skin
Retinoids protect the skin from infection by inducing the production of an endogenous antimicrobial protein.
About The Cover
Online Cover This week features a Research Article that identifies a paracrine signaling circuit between corneal epithelial cells and fibroblasts that is required for the healing of corneal wounds that disrupt the basal lamina. The image is a transmission electron micrograph of a human cornea showing the basal lamina that separates the epithelium from the underlying stroma. [Image: Don W. Fawcett/Science Source]
