Contents

Research Articles

• SOX9 is required for kidney fibrosis and activates NAV3 to drive renal myofibroblast function

  By Sayyid Raza, Elliot Jokl, James Pritchett, Katherine Martin, Kim Su, Kara Simpson, Lindsay Birchall, Aoibheann F. Mullan, Varinder S. Athwal, Daniel T. Doherty, Leo Zeef, Neil C. Henderson, Philip A. Kalra, Neil A. Hanley, Karen Piper Hanley

  Science Signaling02 Mar 2021 Full AccessRestricted Access

  Loss of the transcription factor SOX9 reduces experimentally induced kidney fibrosis in mice.

  • Editor's Summary
  • Abstract
  • Full Text
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  • Supplementary Materials

• A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability

  By Daniela Maier-Begandt, Heather Skye Comstra, Samuel A. Molina, Nenja Krüger, Claire A. Ruddiman, Yen-Lin Chen, Xiaobin Chen, Lauren A. Biwer, Scott R. Johnstone, Alexander W. Lohman, Miranda E. Good, Leon J. DeLalio, Kwangseok Hong, Hannah M. Bacon, Zhen Yan, Swapnil K. Sonkusare, Michael Koval, Brant E. Isakson

  Science Signaling02 Mar 2021 Full AccessRestricted Access

  A pathway underlying the TNFα-induced decrease in endothelial barrier function is found in veins but not arteries.

  • Editor's Summary
  • Abstract
  • Full Text
  • PDF
  • Supplementary Materials