Contents
Vol 1, Issue 14
Contents
Review
- Calpain in the CNS: From Synaptic Function to Neurotoxicity
Physiological activation of calpains may play a role in memory, whereas pathological activation leads to cell death.
Podcast
- Science Signaling Podcast: 08 April 2008
Mutations in the IGF-1 receptor are associated with longer life span in humans.
Editors' Choice
- Shape-Shifting Chemokines
Lymphotactin has two independent, stable, biologically active conformations.
- Synthesizing a Response
Tryptophan aminotransferase in Arabidopsis (TAA1) responds to internal and external signals to catalyze the local production of a precursor of the hormone auxin.
- Complexity in the Bacterial Community
The architecture of the biofilm controls bacterial differentiation.
- Cadherin Learns New Tricks
The extracellular domain of calsyntenin is required for learning in C. elegans.
- Working Back to Pluripotency
A protein necessary for reprogramming skin fibroblasts to pluripotent stem cells is an RNA binding protein that normally inhibits microRNA processing in embryonic cells.
- Nitric Oxide-Mediated Oncogenic Loop
Ras oncogenes act through nitric oxide synthase to promote tumor growth.
