08 April 2008
Vol 1, Issue 14
  • Contents

    • Review

    • Podcast

    • Editors' Choice

      • Shape-Shifting Chemokines

        Lymphotactin has two independent, stable, biologically active conformations.

      • Synthesizing a Response

        Tryptophan aminotransferase in Arabidopsis (TAA1) responds to internal and external signals to catalyze the local production of a precursor of the hormone auxin.

      • Cadherin Learns New Tricks

        The extracellular domain of calsyntenin is required for learning in C. elegans.

      • Working Back to Pluripotency

        A protein necessary for reprogramming skin fibroblasts to pluripotent stem cells is an RNA binding protein that normally inhibits microRNA processing in embryonic cells.

About The Cover

Cover image expansion

COVER This week's issue includes a Review that describes the physiological and pathophysiological activities of calpain in the nervous system. The image depicts activated calpain cleaving a postsynaptic protein. [Image: Christopher Bickel, AAAS]