Contents
Vol 1, Issue 15
Contents
Review
- Eph, a Protein Family Coming of Age: More Confusion, Insight, or Complexity?
Eph receptors and their ephrin ligands coordinate cell-positioning programs during development and oncogenesis.
Journal Club
- GABA Effects on Neurogenesis: An Arsenal of Regulation
GABA regulates neurogenesis in various circumstances.
Editors' Choice
- Bacterial TIR Domains
Bacteria interfere with Toll-like receptor signaling by secreting proteins with TIR domains that compete with the MyD88 adaptor.
- Follow the Endothelin
Endothelin derived from blood vessels helps direct sympathetic neurons to their target organs.
- Keeping Axons on Track
In mice, axons carrying signals from spinal cord to muscle are kept separate from those going in the opposite direction by ephrin signaling between them.
- Slow Breathing
AKAP121 degradation leads to decreased mitochondrial metabolism under hypoxic conditions.
- Balancing Stability and Dynamics
Precise control of adhesive properties is essential for collective migration.
- Bcl2 Blocks DNA Repair
In the nucleus, Bcl2 interacts with apurinic/apyrimidinic endonuclease 1 (APE1) to inhibit DNA repair.
- Radioprotection: Taking the Toll Road
A drug that triggers the pathway that cancer cells use to avoid death can protect healthy cells from the harmful effects of radiation treatment.
- Fast Receptors in Every Respect
Desensitized glutamate receptors are exchanged for functional ones through lateral movement within membranes to help maintain fast excitatory neurotransmission.
