Contents
Vol 1, Issue 30
Contents
Perspective
- A New TRADDition in Intracellular Antiviral Signaling
The tumor necrosis factor (TNF) receptor—associated death domain (TRADD) adaptor protein plays a role in the antiviral response.
Editors' Choice
- Against the CLOCK
SIRT1, an NAD+-dependent histone deacetylase, balances the histone acetyltransferase activity of CLOCK in the control of circadian rhythms.
- Switching from Blue to Green
Terminally differentiated neurons switch from sensing blue light to green light during metamorphosis of the fly larval eye into the adult eyelet, an organ involved in circadian timing.
- Why Aging Muscles Don't Repair
Less Notch antagonism of transforming growth factor-β-mediated Smad3 signaling prevents muscle stem cells from repairing injury in old muscles.
- Regulating Estrogen Receptor’s Cytoplasmic Partners
Arginine methylation of estrogen receptor alpha promotes its interaction with cytoplasmic signaling proteins.
- Finding a Target or Settling Down with One
Two tyrosine residues in the actin-binding protein HS1 play distinct roles in NK cell function.
- Brassinosteroid Signaling
When a plant membrane receptor is activated by a steroid hormone, two kinases are phosphorylated that ultimately regulate gene expression and development.
