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Abstract
This conversation is about research highlighted in the Editors' Choice summaries titled, “A Virulent Response to Losing Your Tail” and “Coupling Secretion with Transcription.” The highlighted articles are Z. Liu, T. Miyashiro, A. Tsou, A. Hsiao, M. Goulian, J. Zhu, Mucosal penetration primes Vibrio cholerae for host colonization by repressing quorum sensing. Proc. Natl. Acad. Sci. U.S.A. 105, 9769–9774 (2008), and S. Raghavan, P. Manzanillo, K. Chan, C. Dovey, J. S. Cox, Secreted transcription factor controls Mycobacterium tuberculosis virulence. Nature 454, 717–721 (2008). (Length: 12 min; file size: 5.62 MB; file format: mp3; location: http://podcasts.aaas.org/science_signaling/ScienceSignaling_080923.mp3)