Editors' ChoiceNeuroscience

Chloride Channel Clinched

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Science Signaling  28 Oct 2008:
Vol. 1, Issue 43, pp. ec371
DOI: 10.1126/scisignal.143ec371

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  • Chloride Currents: Don't Forget ClC-3

    While there is much justified excitement concerning the identification of TMEM16A as a calcium-activated chloride channel (1, 2), I would like to draw attention to the existence of a completely different protein that makes substantial contributions to the transmembrane chloride currents that drive "cell excitability and fluid secretion", as well as many other physiological activities (3). These particular chloride currents a...

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    Competing Interests: None declared.

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