Contents
Vol 1, Issue 44
Contents
Review
- NAADP: A Universal Ca2+ Trigger
NAADP elicits an initial release of calcium, which is subsequently amplified through the action of other calcium messengers.
Editors' Choice
- Sensing When Happy Days Are Here Again
Peptidoglycan fragments released from growing bacteria trigger germination of dormant spores.
- Thrombin Targets Notch Signaling
Cleavage of the Notch ligand Jagged1 by thrombin appears to promote nonclassical release of fibroblast growth factor 1 by inhibiting Notch signaling.
- PRMT Versus Akt for FOXO
FOXO transcriptional activity is promoted by arginine methylation, which blocks phosphorylation by Akt.
- TRPM7 and T Cell Development
A cation channel that conducts both Ca2+ and Mg2+ is unexpectedly required for normal mouse development, specifically for proper maturation of the thymus and T cells.
- Transporter in Action
The structure of a membrane transporter in an open state suggests that inward- and outward-facing cavities reciprocally open and close coordinated by two transmembrane segments.
- Of Glia and Senses
Non-neural glial cells are required for the normal operation of the main sensory organ of a nematode, influencing neuronal shape and function, as well as behavior.
- The Importance of Meeting at the Pole
A feedback loop that integrates multiple signaling mechanisms controls bacterial cell division.
