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vol. 10 no. 461
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History:
- Received July 4, 2016
- Accepted December 16, 2016
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Copyright © 2017, American Association for the Advancement of Science
Research ArticleNeuroscience
Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice
- Jörg Isensee1,*,
- Leonhardt Krahé1,
- Katharina Moeller1,
- Vanessa Pereira2,
- Jane E. Sexton2,
- Xiaohui Sun2,
- Edward Emery2,
- John N. Wood2, and
- Tim Hucho1,*
- 1Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital of Cologne, Robert Koch Str. 10, 50931 Cologne, Germany.
- 2Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.
- ↵*Corresponding author. Email: joerg.isensee{at}uk-koeln.de (J.I.); tim.hucho{at}uk-koeln.de (T.H.)
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Science Signaling 10 Jan 2017:
Vol. 10, Issue 461, eaah4874
DOI: 10.1126/scisignal.aah4874
Vol. 10, Issue 461, eaah4874
DOI: 10.1126/scisignal.aah4874
Jörg Isensee
Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital of Cologne, Robert Koch Str. 10, 50931 Cologne, Germany.
Leonhardt Krahé
Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital of Cologne, Robert Koch Str. 10, 50931 Cologne, Germany.
Katharina Moeller
Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital of Cologne, Robert Koch Str. 10, 50931 Cologne, Germany.
Vanessa Pereira
Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.
Jane E. Sexton
Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.
Xiaohui Sun
Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.
Edward Emery
Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.
John N. Wood
Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.
Tim Hucho
Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital of Cologne, Robert Koch Str. 10, 50931 Cologne, Germany.
