24 January 2017
Vol 10, Issue 463

About The Cover

Cover image expansion

Online Cover This week features a Research Article that describes a critical role for phosphorylation of a specific site in the pore-forming subunit of the L-type calcium channel Cav1.2 in mediating glucose-induced vasoconstriction. Along with the identification of the signaling complex that enables this tissue-specific phosphorylation event, this study has implications for developing treatments for vascular complications associated with diabetes. The image represents a diabetic patient with compromised circulation in the feet. [Image: jorgeantonio/]