Editors' ChoiceImmunology

Paper of note in Science Immunology 2 (7)

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Science Signaling  31 Jan 2017:
Vol. 10, Issue 464, eaam8648
DOI: 10.1126/scisignal.aam8648

This month’s article shows how the complement C5a receptor initiates the recruitment of neutrophils into joint endothelium in a mouse model of arthritis.

ARTHRITIS

Adhering to arthritis

Miyabe et al. show that the complement component C5a causes neutrophils to adhere to joint endothelium to initiate inflammation.

Highlighted Article

    1. Y. Miyabe,
    2. C. Miyabe,
    3. T. T. Murooka,
    4. E. Y. Kim,
    5. G. A. Newton,
    6. N. D. Kim,
    7. B. Haribabu,
    8. F. W. Luscinskas,
    9. T. R. Mempel,
    10. A. D. Luster
    , Complement C5a receptor is the key initiator of neutrophil adhesion igniting immune complex–induced arthritis. Sci. Immunol. 2, eaaj2195 (2017).
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  • Paper of note in Science Immunology 2 (7)

    By John F. Foley

    Science Signaling

    This month’s article shows how the complement C5a receptor initiates the recruitment of neutrophils into joint endothelium in a mouse model of arthritis.

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