28 February 2017
Vol 10, Issue 468

About The Cover

Cover image expansion

Online Cover This week features a Focus Issue on autophagy, the process of cellular self-digestion. This Focus Issue includes a Research Article that reveals how autophagy limits pathological hypertrophy in the heart, a Review on how autophagic responses to stress contribute to cardiometabolic disease, a Review on how mitophagy determines adipocyte cell fate and function, and a Review on how autophagy itself can regulate transcriptional responses to stress. The image shows an ouroboros (a dragon eating its own tail) with an autophagosome for its spine. [Image: Ismail Sergin/Washington University School of Medicine, St. Louis, MO]