Papers of note in Nature 543 (7646)

Annalisa M. VanHook

doi:10.1126/scisignal.aan2960

This week’s articles highlight synaptic organization in sociability, the interactions between a plant and its microbiome, and the role of RNA modification in the response to DNA damage.

HOST-MICROBE INTERACTIONS

Plants prioritize nutrition over defense

Castrillo et al. found that a plant nutrient stress response network shapes the root microbiome and coordinates defense with nutritional stress.

NEUROSCIENCE

Sociability through glutamatergic signaling

Krishnan et al. report that an autism-associated protein impairs sociability in mice by altering glutamatergic synapse organization.

DNA REPAIR

Marking DNA damage with methylated RNA

Xiang et al. found that ultraviolet radiation induces an RNA modification that recruits a DNA repair enzyme.

Highlighted Articles

1. G. Castrillo,
2. P. J. P. L. Teixeira,
3. S. H. Paredes,
4. T. F. Law,
5. L. de Lorenzo,
6. M. E. Feltcher,
7. O. M. Finkel,
8. N. W. Breakfield,
9. P. Mieczkowski,
10. C. D. Jones,
11. J. Paz-Ares,
12. J. L. Dangl
, Root microbiota drive direct integration of phosphate stress and immunity. Nature 543, 513–518 (2017).
OpenUrl
1. V. Krishnan,
2. D. C. Stoppel,
3. Y. Nong,
4. M. A. Johnson,
5. M. J. S. Nadler,
6. E. Ozkaynak,
7. B. L. Teng,
8. I. Nagakura,
9. F. Mohammad,
10. M. A. Silva,
11. S. Peterson,
12. T. J. Cruz,
13. E. M. Kasper,
14. R. Arnaout,
15. M. P. Anderson
, Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1. Nature 543, 507–512 (2017).
OpenUrl
1. Y. Xiang,
2. B. Laurent,
3. C.-H. Hsu,
4. S. Nachtergaele,
5. Z. Lu,
6. W. Sheng,
7. C. Xu,
8. H. Chen,
9. J. Ouyang,
10. S. Wang,
11. D. Ling,
12. P.-H. Hsu,
13. L. Zou,
14. A. Jambhekar,
15. C. He,
16. Y. Shi
, RNA m⁶A methylation regulates the ultraviolet-induced DNA damage response. Nature 543, 573–576 (2017).
OpenUrl

This week’s articles highlight synaptic organization in sociability, the interactions between a plant and its microbiome, and the role of RNA modification in the response to DNA damage.

[1] G. Castrillo,
P. J. P. L. Teixeira,
S. H. Paredes,
T. F. Law,
L. de Lorenzo,
M. E. Feltcher,
O. M. Finkel,
N. W. Breakfield,
P. Mieczkowski,
C. D. Jones,
J. Paz-Ares,
J. L. Dangl
, Root microbiota drive direct integration of phosphate stress and immunity. Nature 543, 513–518 (2017).
OpenUrl

[2] G. Castrillo,

[3] P. J. P. L. Teixeira,

[4] S. H. Paredes,

[5] T. F. Law,

[6] L. de Lorenzo,

[7] M. E. Feltcher,

[8] O. M. Finkel,

[9] N. W. Breakfield,

[10] P. Mieczkowski,

[11] C. D. Jones,

[12] J. Paz-Ares,

[13] J. L. Dangl

[14] V. Krishnan,
D. C. Stoppel,
Y. Nong,
M. A. Johnson,
M. J. S. Nadler,
E. Ozkaynak,
B. L. Teng,
I. Nagakura,
F. Mohammad,
M. A. Silva,
S. Peterson,
T. J. Cruz,
E. M. Kasper,
R. Arnaout,
M. P. Anderson
, Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1. Nature 543, 507–512 (2017).
OpenUrl

[15] V. Krishnan,

[16] D. C. Stoppel,

[17] Y. Nong,

[18] M. A. Johnson,

[19] M. J. S. Nadler,

[20] E. Ozkaynak,

[21] B. L. Teng,

[22] I. Nagakura,

[23] F. Mohammad,

[24] M. A. Silva,

[25] S. Peterson,

[26] T. J. Cruz,

[27] E. M. Kasper,

[28] R. Arnaout,

[29] M. P. Anderson

[30] Y. Xiang,
B. Laurent,
C.-H. Hsu,
S. Nachtergaele,
Z. Lu,
W. Sheng,
C. Xu,
H. Chen,
J. Ouyang,
S. Wang,
D. Ling,
P.-H. Hsu,
L. Zou,
A. Jambhekar,
C. He,
Y. Shi
, RNA m⁶A methylation regulates the ultraviolet-induced DNA damage response. Nature 543, 573–576 (2017).
OpenUrl

[31] Y. Xiang,

[32] B. Laurent,

[33] C.-H. Hsu,

[34] S. Nachtergaele,

[35] Z. Lu,

[36] W. Sheng,

[37] C. Xu,

[38] H. Chen,

[39] J. Ouyang,

[40] S. Wang,

[41] D. Ling,

[42] P.-H. Hsu,

[43] L. Zou,

[44] A. Jambhekar,

[45] C. He,

[46] Y. Shi

Papers of note in Nature 543 (7646)

Highlighted Articles

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