Research ArticleCancer
The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB
- Yukari Okita1,
- Minori Kimura1,
- Rudy Xie1,
- Chen Chen1,
- Larina Tzu-Wei Shen1,
- Yurika Kojima1,
- Hiroyuki Suzuki1,
- Masafumi Muratani2,
- Masao Saitoh3,
- Kentaro Semba4,
- Carl-Henrik Heldin5, and
- Mitsuyasu Kato1,*
- 1Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
- 2Department of Genome Biology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
- 3Department of Biochemistry, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, Japan.
- 4Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku, Tokyo 162-8480, Japan.
- 5Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, Box 595, SE-751 24 Uppsala, Sweden.
- ↵*Corresponding author. Email: mit-kato{at}md.tsukuba.ac.jp
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Sci. Signal. 11 Apr 2017:
Vol. 10, Issue 474, eaak9397
DOI: 10.1126/scisignal.aak9397
