Papers of note in Science 356 (6333)

Annalisa M. VanHook

doi:10.1126/scisignal.aan3880

This week’s articles identify a potential cause for the development of celiac disease and a method for targeting an AMPA receptor agonist to specific neurons.

IMMUNOLOGY

Viruses compound dietary pathology

Bouziat et al. found that a nonpathogenic virus can promote inflammatory immunity to dietary antigens and may be linked to the development of celiac disease (see also Verdu and Caminero).

NEUROSCIENCE

A tailored look at behavioral pharmacology

Shields et al. developed a technique, DART (Drugs Acutely Restricted by Tethering), that rapidly localizes drugs to the surface of specific neurons.

Highlighted Articles

1. R. Bouziat,
2. R. Hinterleitner,
3. J. J. Brown,
4. J. E. Stencel-Baerenwald,
5. M. Ikizler,
6. T. Mayassi,
7. M. Meisel,
8. S. M. Kim,
9. V. Discepolo,
10. A. J. Pruijssers,
11. J. D. Ernest,
12. J. A. Iskarpatyoti,
13. L. M. M. Costes,
14. I. Lawrence,
15. B. A. Palanski,
16. M. Varma,
17. M. A. Zurenski,
18. S. Khomandiak,
19. N. McAllister,
20. P. Aravamudhan,
21. K. W. Boehme,
22. F. Hu,
23. J. N. Samsom,
24. H.-C. Reinecker,
25. S. S. Kupfer,
26. S. Guandalini,
27. C. E. Semrad,
28. V. Abadie,
29. C. Khosla,
30. L. B. Barreiro,
31. R. J. Xavier,
32. A. Ng,
33. T. S. Dermody,
34. B. Jabri
, Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science 356, 44–50 (2017).
OpenUrl Abstract/FREE Full Text
1. E. F. Verdu,
2. A. Caminero
, How infection can incite sensitivity to food. Science 356, 29–30 (2017).
OpenUrl Abstract/FREE Full Text
1. B. C. Shields,
2. E. Kahuno,
3. C. Kim,
4. P. F. Apostolides,
5. J. Brown,
6. S. Lindo,
7. B. D. Mensh,
8. J. T. Dudman,
9. L. D. Lavis,
10. M. R. Tadross
, Deconstructing behavioral neuropharmacology with cellular specificity. Science 356, eaaj2161 (2017).
OpenUrl Abstract/FREE Full Text

This week’s articles identify a potential cause for the development of celiac disease and a method for targeting an AMPA receptor agonist to specific neurons.

[1] R. Bouziat,
R. Hinterleitner,
J. J. Brown,
J. E. Stencel-Baerenwald,
M. Ikizler,
T. Mayassi,
M. Meisel,
S. M. Kim,
V. Discepolo,
A. J. Pruijssers,
J. D. Ernest,
J. A. Iskarpatyoti,
L. M. M. Costes,
I. Lawrence,
B. A. Palanski,
M. Varma,
M. A. Zurenski,
S. Khomandiak,
N. McAllister,
P. Aravamudhan,
K. W. Boehme,
F. Hu,
J. N. Samsom,
H.-C. Reinecker,
S. S. Kupfer,
S. Guandalini,
C. E. Semrad,
V. Abadie,
C. Khosla,
L. B. Barreiro,
R. J. Xavier,
A. Ng,
T. S. Dermody,
B. Jabri
, Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science 356, 44–50 (2017).
OpenUrl Abstract/FREE Full Text

[2] R. Bouziat,

[3] R. Hinterleitner,

[4] J. J. Brown,

[5] J. E. Stencel-Baerenwald,

[6] M. Ikizler,

[7] T. Mayassi,

[8] M. Meisel,

[9] S. M. Kim,

[10] V. Discepolo,

[11] A. J. Pruijssers,

[12] J. D. Ernest,

[13] J. A. Iskarpatyoti,

[14] L. M. M. Costes,

[15] I. Lawrence,

[16] B. A. Palanski,

[17] M. Varma,

[18] M. A. Zurenski,

[19] S. Khomandiak,

[20] N. McAllister,

[21] P. Aravamudhan,

[22] K. W. Boehme,

[23] F. Hu,

[24] J. N. Samsom,

[25] H.-C. Reinecker,

[26] S. S. Kupfer,

[27] S. Guandalini,

[28] C. E. Semrad,

[29] V. Abadie,

[30] C. Khosla,

[31] L. B. Barreiro,

[32] R. J. Xavier,

[33] A. Ng,

[34] T. S. Dermody,

[35] B. Jabri

[36] E. F. Verdu,
A. Caminero
, How infection can incite sensitivity to food. Science 356, 29–30 (2017).
OpenUrl Abstract/FREE Full Text

[37] E. F. Verdu,

[38] A. Caminero

[39] B. C. Shields,
E. Kahuno,
C. Kim,
P. F. Apostolides,
J. Brown,
S. Lindo,
B. D. Mensh,
J. T. Dudman,
L. D. Lavis,
M. R. Tadross
, Deconstructing behavioral neuropharmacology with cellular specificity. Science 356, eaaj2161 (2017).
OpenUrl Abstract/FREE Full Text

[40] B. C. Shields,

[41] E. Kahuno,

[42] C. Kim,

[43] P. F. Apostolides,

[44] J. Brown,

[45] S. Lindo,

[46] B. D. Mensh,

[47] J. T. Dudman,

[48] L. D. Lavis,

[49] M. R. Tadross

Papers of note in Science 356 (6333)

Highlighted Articles

Science Signaling

Article Tools