Papers of note in Nature 544 (7650)

Annalisa M. VanHook

doi:10.1126/scisignal.aan4393

This week’s articles show that vesicle fusion proteins are involved in long-term potentiation and highlight the structural properties that contribute to functional differences between angiotensin II receptors.

NEUROSCIENCE

Postsynaptic vesicle fusion for LTP

Wu et al. show that synaptotagmins are required postsynaptically for recruitment of AMPA receptors during NMDA receptor–dependent long-term potentiation.

BIOCHEMISTRY

Understanding an enigmatic receptor

Zhang et al. report structural features that contribute to the unusual signaling properties of the angiotensin II type 2 receptor (see also Tate).

Highlighted Articles

1. D. Wu,
2. T. Bacaj,
3. W. Morishita,
4. D. Goswami,
5. K. L. Arendt,
6. W. Xu,
7. L. Chen,
8. R. C. Malenka,
9. T. C. Südhof
, Postsynaptic synaptotagmins mediate AMPA receptor exocytosis during LTP. Nature 544, 316–321 (2017).
OpenUrl
1. H. Zhang,
2. G. Won Han,
3. A. Batyuk,
4. A. Ishchenko,
5. K. L. White,
6. N. Patel,
7. A. Sadybekov,
8. B. Zamlynny,
9. M. T. Rudd,
10. K. Hollenstein,
11. A. Tolstikova,
12. T. A. White,
13. M. S. Hunter,
14. U. Weierstall,
15. W. Liu,
16. K. Babaoglu,
17. E. L. Moore,
18. R. D. Katz,
19. J. M. Shipman,
20. M. Garcia-Calvo,
21. S. Sharma,
22. P. Sheth,
23. S. M. Soisson,
24. R. C. Stevens,
25. V. Katritch,
26. V. Cherezov
, Structural basis for selectivity and diversity in angiotensin II receptors. Nature 544, 327–332 (2017).
OpenUrl
1. C. G. Tate
, A receptor that might block itself. Nature 544, 307–308 (2017).
OpenUrl

[1] D. Wu,
T. Bacaj,
W. Morishita,
D. Goswami,
K. L. Arendt,
W. Xu,
L. Chen,
R. C. Malenka,
T. C. Südhof
, Postsynaptic synaptotagmins mediate AMPA receptor exocytosis during LTP. Nature 544, 316–321 (2017).
OpenUrl

[2] D. Wu,

[3] T. Bacaj,

[4] W. Morishita,

[5] D. Goswami,

[6] K. L. Arendt,

[7] W. Xu,

[8] L. Chen,

[9] R. C. Malenka,

[10] T. C. Südhof

[11] H. Zhang,
G. Won Han,
A. Batyuk,
A. Ishchenko,
K. L. White,
N. Patel,
A. Sadybekov,
B. Zamlynny,
M. T. Rudd,
K. Hollenstein,
A. Tolstikova,
T. A. White,
M. S. Hunter,
U. Weierstall,
W. Liu,
K. Babaoglu,
E. L. Moore,
R. D. Katz,
J. M. Shipman,
M. Garcia-Calvo,
S. Sharma,
P. Sheth,
S. M. Soisson,
R. C. Stevens,
V. Katritch,
V. Cherezov
, Structural basis for selectivity and diversity in angiotensin II receptors. Nature 544, 327–332 (2017).
OpenUrl

[12] H. Zhang,

[13] G. Won Han,

[14] A. Batyuk,

[15] A. Ishchenko,

[16] K. L. White,

[17] N. Patel,

[18] A. Sadybekov,

[19] B. Zamlynny,

[20] M. T. Rudd,

[21] K. Hollenstein,

[22] A. Tolstikova,

[23] T. A. White,

[24] M. S. Hunter,

[25] U. Weierstall,

[26] W. Liu,

[27] K. Babaoglu,

[28] E. L. Moore,

[29] R. D. Katz,

[30] J. M. Shipman,

[31] M. Garcia-Calvo,

[32] S. Sharma,

[33] P. Sheth,

[34] S. M. Soisson,

[35] R. C. Stevens,

[36] V. Katritch,

[37] V. Cherezov

[38] C. G. Tate
, A receptor that might block itself. Nature 544, 307–308 (2017).
OpenUrl

[39] C. G. Tate

Papers of note in Nature 544 (7650)

Highlighted Articles

Science Signaling

Article Tools