This week’s articles describe a new hydrogel that promotes chronic wound healing and a way to limit intestinal tissue damage from radiation, chemo, or hematopoietic cell transplant therapies.
WOUND HEALING
Capturing chemokines in chronic wounds
Lohmann et al. show that a heparin-based hydrogel sequesters proinflammatory chemokines, reduces inflammation, and promotes tissue regeneration in chronic wounds.
INTESTINAL INTEGRITY
Innate immune signaling protects the gut
Fischer et al. report that activation of the innate immune pathways mediated by RIG-I or STING protects the gut after irradiation or hematopoietic transplant therapy.