Research ArticleImmunology
Tetraspanin microdomains control localized protein kinase C signaling in B cells
- Malou Zuidscherwoude1,*,
- Vera-Marie E. Dunlock1,*,
- Geert van den Bogaart1,
- Sjoerd J. van Deventer1,
- Alie van der Schaaf1,
- Jenny van Oostrum2,
- Joachim Goedhart3,
- Joanna In ‘t Hout4,
- Günter J. Hämmerling5,
- Satoshi Tanaka6,
- André Nadler7,
- Carsten Schultz8,
- Mark D. Wright9,
- Merel J. W. Adjobo-Hermans2, and
- Annemiek B. van Spriel1,†
- 1Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands.
- 2Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands.
- 3Swammerdam Institute for Life Sciences, Section of Molecular Cytology, van Leeuwenhoek Centre for Advanced Microscopy, University of Amsterdam, 1098 XH Amsterdam, Netherlands.
- 4Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center, 6500 HB Nijmegen, Netherlands.
- 5Department of Molecular Immunology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
- 6Department of Pathology, Sapporo Medical University School of Medicine, 060-8556 Sapporo, Japan.
- 7Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
- 8Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.
- 9Department of Immunology, Monash University, Alfred Medical Research and Education Precinct, Melbourne, Victoria 3004, Australia.
- ↵†Corresponding author. Email: annemiek.vanspriel{at}radboudumc.nl
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Science Signaling 09 May 2017:
Vol. 10, Issue 478, eaag2755
DOI: 10.1126/scisignal.aag2755
