This week’s articles address the role of macrophage metabolic reprogramming in resolving inflammation and an epidermal pattern formation system that is self-organizing and can adjust to fit the size of the tissue.
INFLAMMATION
A way to switch off IBD
Ip et al. found that an interleukin controls a metabolic switch in macrophages that inhibits a signaling pathway, thereby suppressing intestinal inflammation (see also Kabat and Pearce).
NEURODEVELOPMENT
Self-organization for sensory brushes
Corson et al. showed that distributed and flexible patterning combines with cell-cell interactions to establish rows of sensory bristles on the fly thorax.
