This week’s articles demonstrate how T cells search for ligands; a role for the endoplasmic reticulum in the nonclathrin-mediated endocytosis of a growth factor receptor; and growth coupling between distant bacterial colonies that enables the cells to share limited resources.
IMMUNOLOGY
Search and capture in space and time
Cai et al. showed that T cells of the immune system palpate opposing cell surfaces in their search for ligands.
CELL BIOLOGY
ER-PM contacts in nonclathrin endocytosis
Caldieri et al. dissected an alternate mechanism for epidermal growth factor receptor endocytosis (see also Tan and Anderson).
SYSTEMS BIOLOGY
Maximizing growth by sharing
Liu et al. demonstrate how sharing resources can benefit bacterial colonies (see also Gordon).