Research ArticleBiochemistry
Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2
- Zil E. Huma1,
- Julie Sanchez1,
- Herman D. Lim2,
- Jessica L. Bridgford1,2,
- Cheng Huang1,
- Bradyn J. Parker1,
- Jiann G. Pazhamalil1,
- Benjamin T. Porebski1,
- Kevin D. G. Pfleger3,
- J. Robert Lane2,
- Meritxell Canals2,*, and
- Martin J. Stone1,*
- 1Infection and Immunity Program, Monash Biomedicine Discovery Institute, and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.
- 2Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
- 3Molecular Endocrinology and Pharmacology, Harry Perkins Institute of Medical Research, QEII Medical Centre; and Centre for Medical Research, University of Western Australia, Crawley and Dimerix Bioscience Limited, Nedlands, Western Australia, Australia.
- ↵*Corresponding author. Email: martin.stone{at}monash.edu (M.J.S.); meri.canals{at}monash.edu (M.C.)
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Science Signaling 23 May 2017:
Vol. 10, Issue 480, eaai8529
DOI: 10.1126/scisignal.aai8529
