This week’s articles highlight new research that identifies a microRNA decay pathway that promotes cell cycle progression; an interactive atlas of the subcellular localization of thousands of human proteins, which may help refine signaling networks; and a review of symbiotic plant-microbe interactions.
CELL BIOLOGY
Breaking down miRNAs
Elbarbary et al. identify an endonuclease that initiates decay of microRNAs that regulate the cell cycle.
PROTEOMICS
Mapping the proteome
Thul et al. generated the Cell Atlas, an image-based collection of 12,003 proteins and 13 organelles that reveals proteins that exhibit multiple localizations and single-cell variation (see also Horwitz and Johnson).
HOST-MICROBE INTERACTIONS
Taking a look at plant-microbe relationships
Martin et al. review the evolution of plant-symbiont interactions that modulate plant signaling pathways, development, and immunity.