Editors' ChoiceCellular and Molecular Signaling

Papers of note in Science 356 (6340)

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Science Signaling  30 May 2017:
Vol. 10, Issue 481, eaan8309
DOI: 10.1126/scisignal.aan8309

This week’s articles highlight new research that identifies a microRNA decay pathway that promotes cell cycle progression; an interactive atlas of the subcellular localization of thousands of human proteins, which may help refine signaling networks; and a review of symbiotic plant-microbe interactions.


Breaking down miRNAs

Elbarbary et al. identify an endonuclease that initiates decay of microRNAs that regulate the cell cycle.


Mapping the proteome

Thul et al. generated the Cell Atlas, an image-based collection of 12,003 proteins and 13 organelles that reveals proteins that exhibit multiple localizations and single-cell variation (see also Horwitz and Johnson).


Taking a look at plant-microbe relationships

Martin et al. review the evolution of plant-symbiont interactions that modulate plant signaling pathways, development, and immunity.

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