04 July 2017
Vol 10, Issue 486

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows Ca2+ entry into vascular smooth muscle during vasoconstriction activates Ca2+ signaling in the endothelium and vasodilation to protect tissue blood flow. The image shows a pressurized arteriole stained for a voltage-gated Ca2+ channel (yellow) and elastin (white). Vascular smooth muscle cells have vertically aligned nuclei (blue), and endothelial cells have horizontally aligned nuclei (blue). [Image: Pooneh Bagher/University of Oxford, UK]