Papers of note in Science 357 (6347)

Annalisa M. VanHook

doi:10.1126/scisignal.aao3804

This week’s articles highlight a newly discovered DNA repair system and the role of an inherited repressive epigenetic mark in fly embryonic development.

DNA REPAIR

Not-so-sweet DNA damage repaired

Richarme et al. identified a DNA repair system that acts specifically on bases damaged by reaction with by-products of sugar metabolism in the cell (see also Dingler and Patel).

DEVELOPMENTAL BIOLOGY

Intergenerational transcription taming

Zenk et al. demonstrated that inherited repressive epigenetic information controls transcriptional output in offspring.

Highlighted Articles

1. G. Richarme,
2. C. Liu,
3. M. Mihoub,
4. J. Abdallah,
5. T. Leger,
6. N. Joly,
7. J.-C. Liebart,
8. U. V. Jurkunas,
9. M. Nadal,
10. P. Bouloc,
11. J. Dairou,
12. A. Lamouri
, Guanine glycation repair by DJ-1/Park7 and its bacterial homologs. Science 357, 208–211 (2017).
OpenUrl Abstract/FREE Full Text
1. F. A. Dingler,
2. K. J. Patel
, Of sizzling steaks and DNA repair. Science 357, 130–131 (2017).
OpenUrl Abstract/FREE Full Text
1. F. Zenk,
2. E. Loeser,
3. R. Schiavo,
4. F. Kilpert,
5. O. Bogdanović,
6. N. Iovino
, Germ line–inherited H3K27me3 restricts enhancer function during maternal-to-zygotic transition. Science 357, 212–216 (2017).
OpenUrl Abstract/FREE Full Text

View Abstract

This week’s articles highlight a newly discovered DNA repair system and the role of an inherited repressive epigenetic mark in fly embryonic development.

[1] G. Richarme,
C. Liu,
M. Mihoub,
J. Abdallah,
T. Leger,
N. Joly,
J.-C. Liebart,
U. V. Jurkunas,
M. Nadal,
P. Bouloc,
J. Dairou,
A. Lamouri
, Guanine glycation repair by DJ-1/Park7 and its bacterial homologs. Science 357, 208–211 (2017).
OpenUrl Abstract/FREE Full Text

[2] G. Richarme,

[3] C. Liu,

[4] M. Mihoub,

[5] J. Abdallah,

[6] T. Leger,

[7] N. Joly,

[8] J.-C. Liebart,

[9] U. V. Jurkunas,

[10] M. Nadal,

[11] P. Bouloc,

[12] J. Dairou,

[13] A. Lamouri

[14] F. A. Dingler,
K. J. Patel
, Of sizzling steaks and DNA repair. Science 357, 130–131 (2017).
OpenUrl Abstract/FREE Full Text

[15] F. A. Dingler,

[16] K. J. Patel

[17] F. Zenk,
E. Loeser,
R. Schiavo,
F. Kilpert,
O. Bogdanović,
N. Iovino
, Germ line–inherited H3K27me3 restricts enhancer function during maternal-to-zygotic transition. Science 357, 212–216 (2017).
OpenUrl Abstract/FREE Full Text

[18] F. Zenk,

[19] E. Loeser,

[20] R. Schiavo,

[21] F. Kilpert,

[22] O. Bogdanović,

[23] N. Iovino

Papers of note in Science 357 (6347)

Highlighted Articles

Science Signaling

Article Tools