This week’s articles describe new strategies to selectively target therapeutics to tumors.
CANCER THERAPY
A stiff punishment for tumors
Liu et al. engineered mechanoresponsive mesenchymal stem cells to act as vehicles for tumor-targeted drug delivery.
BET-ting on a new drug combination
Yang et al. discovered that inhibiting the epigenetic regulator BET causes a DNA repair deficiency that sensitizes tumors to PARP inhibitors.