Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins

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  Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins

  By Katharine A. White, Diego Garrido Ruiz, Zachary A. Szpiech, Nicolas B. Strauli, Ryan D. Hernandez, Matthew P. Jacobson, Diane L. Barber

  Science Signaling05 Sep 2017

  High intracellular pH in cancer cells enables the oncogenic effects of Arg-to-His mutations in proteins.

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  Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins

  By Katharine A. White, Diego Garrido Ruiz, Zachary A. Szpiech, Nicolas B. Strauli, Ryan D. Hernandez, Matthew P. Jacobson, Diane L. Barber

  Science Signaling05 Sep 2017

  High intracellular pH in cancer cells enables the oncogenic effects of Arg-to-His mutations in proteins.

  • Supplementary Materials

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