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Paper of note in Science Translational Medicine 9 (406)

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Science Signaling  12 Sep 2017:
Vol. 10, Issue 496, eaap9099
DOI: 10.1126/scisignal.aap9099

This week’s article describes how targeted antimicrobials may reduce the virulence of Clostridium difficile infection.


Forcing microbes to make a diff-icult decision

Kirk et al. uncovered important roles for S-layer protein A (SlpA) in Clostridium difficile for the bacteria’s sporulation, resistance to innate immunity effectors, and toxin production.

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