Editors' ChoiceCellular and Molecular Signaling

Papers of note in Nature 549 (7671)

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Science Signaling  19 Sep 2017:
Vol. 10, Issue 497, eaap9538
DOI: 10.1126/scisignal.aap9538

This week’s articles highlight the immune response to intestinal helminth parasites and an mRNA modification that determines cell fate.


Enteric neurons sound the alarm

Cardoso et al. and Klose et al. found that the presence of helminth parasites causes enteric neurons to release a neuropeptide that stimulates innate lymphoid cells to initiate a type 2 inflammatory response.


mRNA modification determines cell fate

Zhang et al. report that a specific biochemical modification of mRNAs influences the specification of the hematopoietic lineage in zebrafish embryos by affecting Notch-mediated cell fate determination.

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