Research ArticleImmunology
Dimerization of the adaptor Gads facilitates antigen receptor signaling by promoting the cooperative binding of Gads to the adaptor LAT
- Sigalit Sukenik1,
- Maria P. Frushicheva2,
- Cecilia Waknin-Lellouche1,
- Enas Hallumi1,
- Talia Ifrach1,
- Rose Shalah1,
- Dvora Beach1,
- Reuven Avidan1,
- Ilana Oz1,
- Evgeny Libman1,*,
- Ami Aronheim3,
- Oded Lewinson4, and
- Deborah Yablonski1,†
- 1Department of Immunology, Ruth and Bruce Rappaport Faculty of Medicine, Technion—Israel Institute of Technology, Haifa 3525433, Israel.
- 2Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
- 3Department of Cell Biology and Cancer Science, Ruth and Bruce Rappaport Faculty of Medicine, Technion—Israel Institute of Technology, Haifa 3525433, Israel.
- 4Department of Biochemistry, Ruth and Bruce Rappaport Faculty of Medicine, Technion—Israel Institute of Technology, Haifa 3525433, Israel.
- ↵†Corresponding author. Email: debya{at}tx.technion.ac.il
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Science Signaling 26 Sep 2017:
Vol. 10, Issue 498, eaal1482
DOI: 10.1126/scisignal.aal1482
