Inhibition of the oncogenic fusion protein EWS-FLI1 causes G₂-M cell cycle arrest and enhanced vincristine sensitivity in Ewing’s sarcoma

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  Inhibition of the oncogenic fusion protein EWS-FLI1 causes G₂-M cell cycle arrest and enhanced vincristine sensitivity in Ewing’s sarcoma

  By Stefan K. Zöllner, Saravana P. Selvanathan, Garrett T. Graham, Ryan M. T. Commins, Sung Hyeok Hong, Eric Moseley, Sydney Parks, Jessica N. Haladyna, Hayriye V. Erkizan, Uta Dirksen, Michael D. Hogarty, Aykut Üren, Jeffrey A. Toretsky

  Science Signaling03 Oct 2017

  A drug sensitizes Ewing’s sarcoma cells to chemotherapy by inducing mitotic arrest and priming the cells for apoptosis.

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  Inhibition of the oncogenic fusion protein EWS-FLI1 causes G₂-M cell cycle arrest and enhanced vincristine sensitivity in Ewing’s sarcoma

  By Stefan K. Zöllner, Saravana P. Selvanathan, Garrett T. Graham, Ryan M. T. Commins, Sung Hyeok Hong, Eric Moseley, Sydney Parks, Jessica N. Haladyna, Hayriye V. Erkizan, Uta Dirksen, Michael D. Hogarty, Aykut Üren, Jeffrey A. Toretsky

  Science Signaling03 Oct 2017

  A drug sensitizes Ewing’s sarcoma cells to chemotherapy by inducing mitotic arrest and priming the cells for apoptosis.

  • Supplementary Materials

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