This week’s articles identify distinct mechanisms of apoptosis in different areas of the germinal center and present an interactive virtual fly embryo that shows the expression of signaling pathway components and other regulatory molecules in individual cells.
IMMUNOLOGY
Light- and dark-zone death dynamics
Mayer et al. found that the selection of germinal center B cells by apoptosis is regulated by microanatomically distinct mechanisms.
SINGLE-CELL TRANSCRIPTOME
Making a fly 3D gene expression blueprint
Karaiskos et al. used single-cell sequencing to generate an interactive database that enables the generation of a 3D virtual fly embryo and gene expression blueprint.