This week’s articles describe ways to potentially treat obesity-associated disorders and prevent sepsis.
OBESITY
A treatment for obesity
Xiong et al. report that delivery of the TGF-β superfamily protein GDF15 treats obesity in mice and monkeys.
SEPSIS
Taking the STING out of sepsis
Zeng et al. show that drugs inhibiting the kinase ALK protect mice against sepsis by attenuating the activation of STING signaling in innate immune cells.
