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Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization
- View ORCID ProfileCarmen L. Krüger1,
- View ORCID ProfileMarie-Theres Zeuner2,
- View ORCID ProfileGraeme S. Cottrell3,
- Darius Widera2, and
- View ORCID ProfileMike Heilemann1,*
- 1Institute of Physical and Theoretical Chemistry, Goethe University, Max von Laue Straße 7, 60438 Frankfurt/Main, Germany.
- 2Stem Cell Biology and Regenerative Medicine, School of Pharmacy, University of Reading, Hopkins Building, Whiteknights, Reading RG6 6UB, UK.
- 3Cellular and Molecular Neuroscience, School of Pharmacy, University of Reading, Hopkins Building, Whiteknights, Reading RG6 6UB, UK.
- ↵*Corresponding author. Email: heilemann{at}chemie.uni-frankfurt.de
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Science Signaling 31 Oct 2017:
Vol. 10, Issue 503, eaan1308
DOI: 10.1126/scisignal.aan1308
Vol. 10, Issue 503, eaan1308
DOI: 10.1126/scisignal.aan1308
Carmen L. Krüger
1Institute of Physical and Theoretical Chemistry, Goethe University, Max von Laue Straße 7, 60438 Frankfurt/Main, Germany.
Marie-Theres Zeuner
2Stem Cell Biology and Regenerative Medicine, School of Pharmacy, University of Reading, Hopkins Building, Whiteknights, Reading RG6 6UB, UK.
Graeme S. Cottrell
3Cellular and Molecular Neuroscience, School of Pharmacy, University of Reading, Hopkins Building, Whiteknights, Reading RG6 6UB, UK.
Darius Widera
2Stem Cell Biology and Regenerative Medicine, School of Pharmacy, University of Reading, Hopkins Building, Whiteknights, Reading RG6 6UB, UK.
Mike Heilemann
1Institute of Physical and Theoretical Chemistry, Goethe University, Max von Laue Straße 7, 60438 Frankfurt/Main, Germany.