Research ArticleFRAGILE X SYNDROME
Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome
- View ORCID ProfileAlexander Pyronneau1,
- Qionger He2,
- View ORCID ProfileJee-Yeon Hwang1,
- View ORCID ProfileMorgan Porch1,
- View ORCID ProfileAnis Contractor2,3, and
- View ORCID ProfileR. Suzanne Zukin1,*
- 1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.
- 2Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
- 3Department of Neurobiology, Weinberg College of Arts and Sciences, Northwestern University, Evanston, IL 60208, USA.
- ↵*Corresponding author. Email: suzanne.zukin{at}einstein.yu.edu
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Science Signaling 07 Nov 2017:
Vol. 10, Issue 504, eaan0852
DOI: 10.1126/scisignal.aan0852
Vol. 10, Issue 504, eaan0852
DOI: 10.1126/scisignal.aan0852
Alexander Pyronneau
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.
Qionger He
2Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Jee-Yeon Hwang
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.
Morgan Porch
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.
Anis Contractor
2Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
3Department of Neurobiology, Weinberg College of Arts and Sciences, Northwestern University, Evanston, IL 60208, USA.
R. Suzanne Zukin
1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.
