Papers of note in Science Translational Medicine 9 (418)

Leslie K. Ferrarelli

doi:10.1126/scisignal.aar6003

This week’s articles describe a way to treat or prevent pulmonary distress and a way to boost treatments against anemia.

ISCHEMIA/REPERFUSION INJURY

Protecting the lungs with irisin

Chen et al. describe how the myokine irisin protects the lungs from ischemic damage by promoting mitochondrial function in response to oxidative stress.

ANEMIA

The body’s stop-gap solution for anemia

Mayer et al. show that activating an arginine vasopressin receptor jump-starts the replenishment of red blood cells in animal models of anemia treated with erythropoietin.

Highlighted Articles

1. K. Chen,
2. Z. Xu,
3. Y. Liu,
4. Z. Wang,
5. Y. Li,
6. X. Xu,
7. C. Chen,
8. T. Xia,
9. Q. Liao,
10. Y. Yao,
11. C. Zeng,
12. D. He,
13. Y. Yang,
14. T. Tan,
15. J. Yi,
16. J. Zhou,
17. H. Zhu,
18. J. Ma,
19. C. Zeng
, Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury. Sci. Transl. Med. 9, eaao6298 (2017).
OpenUrl Abstract/FREE Full Text
1. B. Mayer,
2. K. Németh,
3. M. Krepuska,
4. V. D. Myneni,
5. D. Maric,
6. J. F. Tisdale,
7. M. M. Hsieh,
8. N. Uchida,
9. H.-J. Lee,
10. M. J. Nemeth,
11. K. Holmbeck,
12. C. T. Noguchi,
13. H. Rogers,
14. S. Dey,
15. A. Hansen,
16. J. Hong,
17. I. Chow,
18. S. Key,
19. I. Szalayova,
20. J. Pagani,
21. K. Markó,
22. I. McClain-Caldwell,
23. L. Vitale-Cross,
24. W. S. Young,
25. M. J. Brownstein,
26. É. Mezey
, Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia. Sci. Transl. Med. 9, eaao1632 (2017).
OpenUrl Abstract/FREE Full Text

View Abstract

[1] K. Chen,
Z. Xu,
Y. Liu,
Z. Wang,
Y. Li,
X. Xu,
C. Chen,
T. Xia,
Q. Liao,
Y. Yao,
C. Zeng,
D. He,
Y. Yang,
T. Tan,
J. Yi,
J. Zhou,
H. Zhu,
J. Ma,
C. Zeng
, Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury. Sci. Transl. Med. 9, eaao6298 (2017).
OpenUrl Abstract/FREE Full Text

[2] K. Chen,

[3] Z. Xu,

[4] Y. Liu,

[5] Z. Wang,

[6] Y. Li,

[7] X. Xu,

[8] C. Chen,

[9] T. Xia,

[10] Q. Liao,

[11] Y. Yao,

[12] C. Zeng,

[13] D. He,

[14] Y. Yang,

[15] T. Tan,

[16] J. Yi,

[17] J. Zhou,

[18] H. Zhu,

[19] J. Ma,

[20] C. Zeng

[21] B. Mayer,
K. Németh,
M. Krepuska,
V. D. Myneni,
D. Maric,
J. F. Tisdale,
M. M. Hsieh,
N. Uchida,
H.-J. Lee,
M. J. Nemeth,
K. Holmbeck,
C. T. Noguchi,
H. Rogers,
S. Dey,
A. Hansen,
J. Hong,
I. Chow,
S. Key,
I. Szalayova,
J. Pagani,
K. Markó,
I. McClain-Caldwell,
L. Vitale-Cross,
W. S. Young,
M. J. Brownstein,
É. Mezey
, Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia. Sci. Transl. Med. 9, eaao1632 (2017).
OpenUrl Abstract/FREE Full Text

[22] B. Mayer,

[23] K. Németh,

[24] M. Krepuska,

[25] V. D. Myneni,

[26] D. Maric,

[27] J. F. Tisdale,

[28] M. M. Hsieh,

[29] N. Uchida,

[30] H.-J. Lee,

[31] M. J. Nemeth,

[32] K. Holmbeck,

[33] C. T. Noguchi,

[34] H. Rogers,

[35] S. Dey,

[36] A. Hansen,

[37] J. Hong,

[38] I. Chow,

[39] S. Key,

[40] I. Szalayova,

[41] J. Pagani,

[42] K. Markó,

[43] I. McClain-Caldwell,

[44] L. Vitale-Cross,

[45] W. S. Young,

[46] M. J. Brownstein,

[47] É. Mezey

Papers of note in Science Translational Medicine 9 (418)

Highlighted Articles

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