eLetters is an online forum for ongoing peer review. Submission of eLetters are open to all. Please read our Terms of Service before submitting your own eLetter.
Research ArticleStress responses
The endoplasmic reticulum–residing chaperone BiP is short-lived and metabolized through N-terminal arginylation
- View ORCID ProfileSang Mi Shim1,2,
- Ha Rim Choi1,2,
- View ORCID ProfileKi Woon Sung1,2,
- View ORCID ProfileYoon Jee Lee1,2,
- View ORCID ProfileSung Tae Kim1,2,3,
- Daeho Kim1,4,
- View ORCID ProfileSu Ran Mun1,2,
- Joonsung Hwang5,
- View ORCID ProfileHyunjoo Cha-Molstad5,
- View ORCID ProfileAaron Ciechanover1,6,
- View ORCID ProfileBo Yeon Kim5,*, and
- View ORCID ProfileYong Tae Kwon1,2,7,*
- 1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
- 2Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
- 3Center for Pharmacogenetics and Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.
- 4Department of Biophysics and Chemical Biology, College of Natural Sciences, Seoul National University, Seoul 08826, Republic of Korea.
- 5World Class Institute, Korea Research Institute of Bioscience and Biotechnology, Ochang, Cheongwon 28116, Republic of Korea.
- 6Tumor and Vascular Biology Research Center, Rappaport Faculty of Medicine and Research Institute, Technion–Israel Institute of Technology, Haifa 31096, Israel.
- 7Ischemic/Hypoxic Disease Institute, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
- ↵*Corresponding author. Email: yok5{at}snu.ac.kr (Y.T.K.); bykim{at}kribb.re.kr (B.Y.K.)
See allHide authors and affiliations
Science Signaling 02 Jan 2018:
Vol. 11, Issue 511, eaan0630
DOI: 10.1126/scisignal.aan0630
Vol. 11, Issue 511, eaan0630
DOI: 10.1126/scisignal.aan0630
Sang Mi Shim
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
2Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
Ha Rim Choi
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
2Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
Ki Woon Sung
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
2Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
Yoon Jee Lee
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
2Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
Sung Tae Kim
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
2Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
3Center for Pharmacogenetics and Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Daeho Kim
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
4Department of Biophysics and Chemical Biology, College of Natural Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Su Ran Mun
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
2Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
Joonsung Hwang
5World Class Institute, Korea Research Institute of Bioscience and Biotechnology, Ochang, Cheongwon 28116, Republic of Korea.
Hyunjoo Cha-Molstad
5World Class Institute, Korea Research Institute of Bioscience and Biotechnology, Ochang, Cheongwon 28116, Republic of Korea.
Aaron Ciechanover
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
6Tumor and Vascular Biology Research Center, Rappaport Faculty of Medicine and Research Institute, Technion–Israel Institute of Technology, Haifa 31096, Israel.
Bo Yeon Kim
5World Class Institute, Korea Research Institute of Bioscience and Biotechnology, Ochang, Cheongwon 28116, Republic of Korea.
Yong Tae Kwon
1Protein Metabolism Medical Research Center, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
2Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
7Ischemic/Hypoxic Disease Institute, College of Medicine, Seoul National University, Seoul 03080, Republic of Korea.
Submit a Response to This Article
No eLetters have been published for this article.