23 January 2018
Vol 11, Issue 514

About The Cover

Cover image expansion

Online Cover This week features a Research Article that structurally defines a cavity in the ion channel TRPA1 that critically coordinates the complex manner in which the channel's sensitivity is regulated and in which alterations may underlie chronic pain and other disorders. The image shows a docking model of the channel with phosphoinositides. [Image: Zimova et al., Science Signaling ]