06 February 2018
Vol 11, Issue 516

About The Cover

Cover image expansion

Online Cover This week features a Research Article that shows that a specific subset of G protein–coupled receptors reduces the sensitivity of cells to the morphogen Sonic Hedgehog. The image shows the Hedgehog signal transducer Smoothened (red) localized to the cilia of cells in the embryonic mouse spinal cord. [Image: Jennifer H. Kong, Departments of Medicine and Biochemistry, Stanford University School of Medicine, USA]