Research ArticleDevelopment
The unfolded protein response regulator ATF6 promotes mesodermal differentiation
- Heike Kroeger1,
- Neil Grimsey2,
- Ryan Paxman3,
- Wei-Chieh Chiang1,
- Lars Plate3,4,
- Ying Jones5,
- Peter X. Shaw6,
- JoAnn Trejo2,
- Stephen H. Tsang7,
- Evan Powers3,
- Jeffery W. Kelly3,
- R. Luke Wiseman3, and
- Jonathan H. Lin1,8,*
- 1Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA.
- 2Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.
- 3Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.
- 4Departments of Chemistry and Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
- 5Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
- 6Department of Ophthalmology, University of California, San Diego, La Jolla, CA 92093, USA.
- 7Jonas Children’s Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Departments of Ophthalmology, Pathology and Cell Biology, Edward S. Harkness Eye Institute, New York Presbyterian Hospital, Columbia University, New York, NY 10032, USA.
- 8VA San Diego Healthcare System, San Diego, CA 92161, USA.
- ↵*Corresponding author. Email: jlin{at}ucsd.edu
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Science Signaling 13 Feb 2018:
Vol. 11, Issue 517, eaan5785
DOI: 10.1126/scisignal.aan5785
Vol. 11, Issue 517, eaan5785
DOI: 10.1126/scisignal.aan5785
Heike Kroeger
Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA.
Neil Grimsey
Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.
Ryan Paxman
Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.
Wei-Chieh Chiang
Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA.
Lars Plate
Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.Departments of Chemistry and Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Ying Jones
Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Peter X. Shaw
Department of Ophthalmology, University of California, San Diego, La Jolla, CA 92093, USA.
JoAnn Trejo
Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.
Stephen H. Tsang
Jonas Children’s Vision Care and Bernard & Shirlee Brown Glaucoma Laboratory, Departments of Ophthalmology, Pathology and Cell Biology, Edward S. Harkness Eye Institute, New York Presbyterian Hospital, Columbia University, New York, NY 10032, USA.
Evan Powers
Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.
Jeffery W. Kelly
Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.
R. Luke Wiseman
Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA 92037, USA.
Jonathan H. Lin
Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA.VA San Diego Healthcare System, San Diego, CA 92161, USA.
