Research ArticleCancer
Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple
- View ORCID ProfileNicolas Aznar1,*,†,‡,
- View ORCID ProfileJason Ear1,*,
- Ying Dunkel1,
- Nina Sun1,
- View ORCID ProfileKendall Satterfield1,
- Fang He1,§,
- Nicholas A. Kalogriopoulos1,
- Inmaculada Lopez-Sanchez1,
- Majid Ghassemian2,
- Debashis Sahoo3,4,
- View ORCID ProfileIrina Kufareva5, and
- View ORCID ProfilePradipta Ghosh1,6,7,†
- 1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
- 2Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
- 3Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
- 4Department of Computer Science and Engineering, Jacobs School of Engineering, University of California, San Diego, La Jolla, CA 92093, USA.
- 5Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
- 6Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
- 7Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
- ↵†Corresponding author. Email: nicolas.aznar{at}inserm.fr (N.A.); prghosh{at}ucsd.edu (P.G.)
↵* These authors contributed equally to this work.
↵‡ Present address: Cancer Research Center of Lyon, Centre Léon Bérard 28, rue Laënnec 69373, Lyon, Cedex 08, France.
↵§ Present address: Center of Infectious Diseases, West China Hospital and Division of Infectious Diseases, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, Sichuan, PR China.
See allHide authors and affiliations
Science Signaling 27 Feb 2018:
Vol. 11, Issue 519, eaao4220
DOI: 10.1126/scisignal.aao4220
Vol. 11, Issue 519, eaao4220
DOI: 10.1126/scisignal.aao4220
Nicolas Aznar
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Jason Ear
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Ying Dunkel
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Nina Sun
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Kendall Satterfield
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Fang He
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Nicholas A. Kalogriopoulos
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Inmaculada Lopez-Sanchez
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Majid Ghassemian
2Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Debashis Sahoo
3Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
4Department of Computer Science and Engineering, Jacobs School of Engineering, University of California, San Diego, La Jolla, CA 92093, USA.
Irina Kufareva
5Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
Pradipta Ghosh
1Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
6Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
7Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.
