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Research ArticleIon Channels
mTORC1 controls lysosomal Ca2+ release through the two-pore channel TPC2
- View ORCID ProfileOluseye A. Ogunbayo1,
- Jingxian Duan1,
- View ORCID ProfileJian Xiong2,
- View ORCID ProfileQiaochu Wang2,
- View ORCID ProfileXinghua Feng2,
- View ORCID ProfileJianjie Ma3,
- View ORCID ProfileMichael X. Zhu2, and
- View ORCID ProfileA. Mark Evans1,*
- 1Centres for Discovery Brain Sciences and Cardiovascular Sciences, Biomedical Sciences, Edinburgh Medical School, University of Edinburgh, Edinburgh, EH8 9XD Scotland, UK.
- 2Department of Integrative Biology and Pharmacology, McGovern Medical School, Program in Biochemistry and Cell Biology, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
- 3Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
- ↵*Corresponding author. Email: mark.evans{at}ed.ac.uk
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Science Signaling 10 Apr 2018:
Vol. 11, Issue 525, eaao5775
DOI: 10.1126/scisignal.aao5775
Vol. 11, Issue 525, eaao5775
DOI: 10.1126/scisignal.aao5775
Oluseye A. Ogunbayo
1Centres for Discovery Brain Sciences and Cardiovascular Sciences, Biomedical Sciences, Edinburgh Medical School, University of Edinburgh, Edinburgh, EH8 9XD Scotland, UK.
Jingxian Duan
1Centres for Discovery Brain Sciences and Cardiovascular Sciences, Biomedical Sciences, Edinburgh Medical School, University of Edinburgh, Edinburgh, EH8 9XD Scotland, UK.
Jian Xiong
2Department of Integrative Biology and Pharmacology, McGovern Medical School, Program in Biochemistry and Cell Biology, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Qiaochu Wang
2Department of Integrative Biology and Pharmacology, McGovern Medical School, Program in Biochemistry and Cell Biology, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Xinghua Feng
2Department of Integrative Biology and Pharmacology, McGovern Medical School, Program in Biochemistry and Cell Biology, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Jianjie Ma
3Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.
Michael X. Zhu
2Department of Integrative Biology and Pharmacology, McGovern Medical School, Program in Biochemistry and Cell Biology, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
A. Mark Evans
1Centres for Discovery Brain Sciences and Cardiovascular Sciences, Biomedical Sciences, Edinburgh Medical School, University of Edinburgh, Edinburgh, EH8 9XD Scotland, UK.
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